This Mississippi pot roast instant pot recipe will warm your heart every time. It’s so rich in flavor, not to mention tender. This recipe can be enjoyed with my garlic butter mashed potatoes. I am not trying to brag, but once you taste this recipe, you will continue making this recipe repeatedly.

Instant pot Mississippi Roast

What is instant pot Mississippi roast?

Mississippi pot roast instant pot is usually made with Chuck roast. Which can usually be found in your local grocery store. The ingredients in this pot roast are simple and easy to find. Another thing that I would like to mention is that this recipe is also keto friendly. You would call that recipe keto Mississippi pot roast. A Mississippi pot roast can be cooked in a slow cooker, stovetop, or in n instant pot. Which is what I did. I also made this recipe with keto-friendly hints why I gave it the name keto Mississippi post roast.

Instant Pot Mississippi Roast
Instant Pot Mississippi Roast

What are the ingredients for instant pot Mississippi roast

Boneless Beef Roast




Garlic Powder

Ranch Dressing Mix

Pepperoncini Peppers

Beef Broth

Vegetable Oil

McCormick Brown Gravy

Those ingredients can all be found at your local grocery store.

pot roast
Check out this slow cooker pot roast

What is the Mississippi pot roast?

A pot roast is when you purchase a cut of beef. Once you purchase the beef, season and sear the meat on both sides, making sure the meat is brown before transferring it to either your slow cooker or instant pot. I placed my keto Mississippi pot roast in an instant pot. The instant pot took about 1 hour to steam, but a pot roast can take well over 5 hours when cooked in a slow cooker. I have made my pot roast in a slow cooker. Let me tell you, both the instant pot and the slow cooker came out amazing!

Is the Mississippi pot roast keto-friendly

Yes, Mississippi pot roast is keto friendly and shouldn’t throw you out of ketosis when consumed in moderation. This recipe is high in protein but not so high in carbohydrates. It’s nothing wrong with carbohydrates. It’s just better for us to stay away from the simple carbs. Things like soda, burgers, fries, chips, and any junk food you can name.

 These types of food spike your sugar levels. The simple carbs boost energy, and you crash and become hungry more quickly. You also have no more energy, but complex carbs do the opposite. They take longer to break down in return, leaving you less hungry.

Can you cook a Mississippi pot roast in an instant pot?

I know you are used to seeing people put their pot roast in a Dutch oven or a slow cooker, but what if I told you that you could cut that cooking time in more than half by first searing your meat on both sides, stovetop? Once you do that, you will place the roast into the instant pot. After that, you want to add the remaining ingredients into the pot. Turn the timer to 1 hour and let the magic happen!! So, to answer your question. Yes, you can cook a Mississippi pot roast in an instant pot.

Tips: if you have never used an instant pot before, please follow a structured YouTube video so that no accidents will happen. Instant pots can be very dangerous when not operated correctly.

How to make

Instant pot Mississippi pot roast must be one of my favorite meals because it’s a no-mess hassle, and the steps in this recipe are simple. If you blank your fast, you just might miss something. So, here we go. Firstly, you want to season your meat on both sides once you have done this, place your meat flat into a preheated cast iron, buttered pan. Once you have placed the roast beef into the cast iron pan, allow it to cook until the cast iron pan releases the meat. Now, continue to the other side. Now that you are done with all your searing. Place your roast into your instant pot along with the rest of the ingredients. Add the top on, set the timer, and enjoy a juicy instant pot roast.

Seared Mississippi Pot Roast

What to serve with Mississippi pot roast

I serve this instant pot Mississippi roast with a ton of different sides. It just depends on what you want to eat that day. My favorite side with this instant pot meal is my roasted broccoli which is very keto and low-carb friendly. You can’t go wrong with this meal. You are going to be getting in your share of protein.

How to store instant pot Mississippi pot roast

You will need to get an airtight storage container. Place all your leftover roast beef into the container. You can store this roast beef in the refrigerator for up to 4 days. If you freeze the leftover roast, it can last in the freezer for up to 2 months or more.

How to reheat

To reheat this recipe in a microwave, just add the beef to a microwave-safe pan. Once you have done so, add the meat to the microwave for one minute and 30 seconds. After that, your food should be good and warm. You can also use the oven. If you have any left-over juice add that to the beef as well. Next, add the aluminum foil over the top of the oven-safe pan. Place the meat in a preheated oven of 325 degrees for 25 minutes or until the roast is warm.

If you enjoyed this quick and easy keto-friendly meal. Then you will love my low carbs/keto-friendly zucchini fries. You can also add one of my protein-pack chicken meals.

Tried this recipe…. tag me on Instagram @ronalyntalston or leave a review. I would love to hear from you.

Here is a dessert idea to go with this recipe. Air fryer s'mores.

Instant pot Mississippi Roast

The Best Instant Pot Mississippi Roast

This Mississippi pot roast instant pot recipe will warm your heart every time. It’s so rich in flavor, not to mention tender. This recipe can be enjoyed with my garlic butter mashed potatoes. I am not trying to brag, but once you taste this recipe, you will continue making this recipe repeatedly.
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Course: Main Course
Cuisine: American
Prep Time: 10 minutes
Cook Time: 1 hour
Total Time: 1 hour 10 minutes
Calories: 3292kcal


  • 4 LB Beef Roast
  • 1 Stick Butter
  • ¼ Teaspoon Salt
  • ¼ Teaspoon Pepper
  • ¼ Teaspoon Garlic Powder
  • 1 Pack Ranch Dressing Mix
  • 3-4 Pepperoncini Peppers
  • 1 Gravy packet
  • ½ Cup Beef Broth
  • 2 Tbsp Vegetable Oil


  • With a piece of paper towel pat dry your roast then season both sides
    4 LB Beef Roast
  • Season your roast on both sides
    ¼ Teaspoon Salt, ¼ Teaspoon Garlic Powder, ¼ Teaspoon Pepper
  • Press sauté on the instant post and allow the vegetable oil to heat up.
    2 Tbsp Vegetable Oil
  • Add in your roast. Allow to sear for 5 on one side then flip. Then turn to the other side and allow that to sauté for another 5 minutes.
  • Carefully remove the meat from the instant pot.
  • Add your beef broth to the instant pot
    ½ Cup Beef Broth
  • Add in your meat, peppers, packets, and butter.
    1 Stick Butter, 3-4 Pepperoncini Peppers, 1 Gravy packet, 1 Pack Ranch Dressing Mix
  • Place the lid onto the instant pot
  • Set the timer for 60 minutes on high
  • When the button pops up on the instant pot your are done
  • Remove the meat from the pot and enjoy


Serving: 1g | Calories: 3292kcal | Carbohydrates: 3g | Protein: 350g | Fat: 209g | Saturated Fat: 92g | Polyunsaturated Fat: 17g | Monounsaturated Fat: 106g | Trans Fat: 12g | Cholesterol: 1252mg | Sodium: 2502mg | Potassium: 6182mg | Fiber: 1g | Sugar: 1g | Vitamin A: 341IU | Vitamin C: 25mg | Calcium: 324mg | Iron: 38mg